Fluoride
This is hardly new, fluoride has been added to some toothpastes for many decades. It is often added to drinking water too. It lowers decay issues in teeth, though there is some controversy.
Swallowing large amount of fluoride can be harmful, but large amounts of many essential nutrients are also harmful if swallowed. Fluoride is present in many foods. As toothpaste and mouthwash only contain small amounts of fluoride and should not be swallowed this is not a major issue.

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Triclosan
This is thought to be an antibacterial agent, useful in reducing gingivitis. Use of Tirclosan is slightly controversial; it is not been proven effective. It might react with chlorine in a way that is harmful.
Zinc Chloride
This is also an antibacterial agent that reduces gingivitis.

Xylitol
This is an alternative sweetener derived from plant bark. Unlike sugar it discourages bacteria growth. It seems to reduce dental decay, though the evidence is still new and controversial. But most experts agree that it at least doesn’t make matter worse.
Xylitol is sweet, and may encourage children to brush their teeth.

Cashews
These are known to reduce dental decay. Do not be surprised if they soon find their way into toothpaste.

Cocoa
This raw ingredient for chocolate is very healthy, providing that it is not combined with sugar. It will reduce bacteria and dental decay, but the only toothpastes that use cocoa (or cacoa, the raw form of the bean) have been prohibitively expensive. As cocoa is a stimulant it is not ideal for using before sleep.

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